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Safety Information

495414

Sigma-Aldrich

1-Oleoyl-2-acetyl-sn-glycerol

Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C.

Synonym(s):

1-Oleoyl-2-acetyl-sn-glycerol, OAG, PKC Activator III

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About This Item

Empirical Formula (Hill Notation):
C23H42O5
CAS Number:
86390-77-4
Molecular Weight:
398.58
MDL number:
MFCD00166985
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥97% (HPLC)

form

oil

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

DMSO: soluble
ethanol: soluble

format

neat

shipped in

ambient

storage temp.

−20°C

InChI

1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1

InChI key

PWTCCMJTPHCGMS-YRBAHSOBSA-N

General description

Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C. Also a stimulator of secretion and aggregation in blood platelets.
Note: 1 set = 10 x 500 µg.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Ca2+-dependent protein kinase C
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Reconstitution

Unstable in solution; reconstitute just prior to use. The material can be dissolved in chloroform, aliquoted, dried under a stream of nitrogen, and stored at -20°C.

Other Notes

Florin-Christensen, J. 1993. Biochem. J.289, 783.
Benz, I., et al. 1992. J. Membr. Biol. 130, 183.
Haeffner, E.W., and Wittmann, U. 1992. J. Lipid Mediat.5, 237.
Gilmore, T., and Martin, G.S. 1983. Nature306, 487.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

495414-MG:
495414-25MG:
495414-5MG:
495414-1SET:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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