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Key Documents

Safety Information

475828

Sigma-Aldrich

β₂-Microglobulin, Human, Recombinant, E. coli

Synonym(s):

rhβ₂M

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.25

form

lyophilized

Quality Level

100

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

solubility

aqueous buffer: soluble

shipped in

wet ice

storage temp.

−20°C

General description

Recombinant, human β2-microglobulin fused at the N-terminus to a His•Tag sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.
Recombinant, human β2-microglobulin fused at the N-terminus to a His•Tag sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

single band by SDS-PAGE

Other Notes

Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613.
Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

475828-1RMG:
475828-1MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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