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Key Documents

Safety Information

437644

Sigma-Aldrich

Lipoproteins, Low Density, Human Plasma

Synonym(s):

LDL

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.25

Assay

≥95% (of total lipoprotein content, electrophoresis)

Quality Level

100

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

do not freeze
protect from light

shipped in

wet ice

storage temp.

2-8°C

General description

A 10 mg vial contains ~2 mg of protein.
Native low density lipoproteins from human plasma. Cholesterol-carrier lipoprotein responsible for delivery of lipids (cholesterol) from liver to tissues. (Composition: 78-81% lipid; 19-22% protein. Note: 10 mg vial contains 2 mg of protein.)
Native low density lipoproteins from human plasma. Cholesterol-carrier lipoprotein responsible for delivery of lipids (cholesterol) from liver to tissues. Composition: 78-81% lipid; 19-22% protein.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 150 mM NaCl, 0.01% EDTA, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

This product does not contain preservatives, so it is recommended that it be used under a laminar flow hood. Following initial use, this product is stable for 1 week at 2-8°C.

Other Notes

Foster, J.D., et al. 1993. Endocrinology132, 337.
Retsky, K.L., et al. 1993. J. Biol. Chem. 268, 1304.
Fielding, C.J. 1992. FASEB J. 6, 3162.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

437644-MG:
437644-10MG:
437644-0MG:
437644-500MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jiawei Chen et al.
The Biochemical journal, 393(Pt 1), 255-265 (2005-09-22)
LOX-1, a receptor for ox-LDL (oxidized low-density lipoprotein), has recently been determined to play a critical role in the progression of atherosclerosis. LOX-1 expression (mRNA and protein) has been shown to be up-regulated by pro-atherogenic stimuli, such as ox-LDL and
Jean Baptiste Nyandwi et al.
International journal of molecular medicine, 49(5) (2022-03-23)
Endothelial dysfunction during diabetes has been previously reported to be at least in part attributed to increased oxidized low‑density lipoprotein (oxLDL) levels mediated by high glucose (HG) levels. Endothelial inflammation increases the adhesiveness of monocytes to the endothelium in addition
Lee D Chaves et al.
JCI insight, 6(11) (2021-04-30)
Patients with chronic kidney disease (CKD) and end-stage renal disease suffer from increased cardiovascular events and cardiac mortality. Prior studies have demonstrated that a portion of this enhanced risk can be attributed to the accumulation of microbiota-derived toxic metabolites, with

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