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Safety Information

437628

Sigma-Aldrich

Lipopolysaccharide

from Salmonella minnesota, , lyophilized, TLR4 signaling stimulator, Calbiochem

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.77

product name

Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re), Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins.

Quality Level

100

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

0.5% triethylamine: 1 mg/mL
water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Harmful (C)

Preparation Note

Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H₂O.

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months.

Other Notes

Hirschfeld, M., et al. 2000. J. Immunol.165, 618.
Tapping, R.I., et al. 2000. J. Immunol.165, 5780.
Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

437628-MG:
437628-1MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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