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341492

Sigma-Aldrich

FeTPPS

A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro.

Synonym(s):

FeTPPS, 5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride

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About This Item

Empirical Formula (Hill Notation):
C44H28ClFeN4O12S4
Molecular Weight:
1024.27
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥95% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

color

dark brown

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

General description

A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a selective peroxynitrite scavenger and decomposition catalyst. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.
A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.

Biochem/physiol Actions

Cell permeable: no
EC50 = 5 µM for cytoprotection against peroxynitrite
Primary Target
Selective peroxynitrite scavenger
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.

Other Notes

Imam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci.914, 157.
Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

341492-MG:
341492-0GM:
341492-25MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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