Skip to Content
Merck
All Photos(1)

Key Documents

Safety Information

324504

Millipore

EDTA

ULTROL® Grade, 500 mM Solution, pH 8.0

Synonym(s):

EDTA, 500 mM Solution, pH 8.0, ULTROL® Grade

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H16N2O8
CAS Number:
60-00-4
Molecular Weight:
292.24
MDL number:
MFCD00003541
UNSPSC Code:
12352107
NACRES:
NA.25

Quality Level

100

form

solution

reaction suitability

reagent type: chelator

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

concentration

500 mM

color

colorless to pale yellow

pH

8

shipped in

ambient

storage temp.

10-30°C

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

Related Categories

General description

A useful agent for radioimmunoimaging.
Ethylenediaminetetraacetic acid (EDTA) is a metal chelating agent, which is used in treating patients with heavy-metal poisonings like lead or mercury. It is also used to minimize the non-specific serum protein interactions in enzyme immunoassays. Due to its ability to inhibit protein agglutination, it is useful to make blood/plasma samples and in immunoanalysis to detect CD3 cells. EDTA combines with buffers or ionic salts to stimulate the immune cells in the blood samples. It is used in multiple aspects to treat and analyze psoriasis. EDTA functions as an antioxidant to combat psoriasis, while it is also used to understand the disease at a molecular level.

Application

EDTA, 500 mM Solution, pH 8.0, ULTROL® Grade has been used along with phosphate buffer saline (PBS) for cell disruption to harvest crypts in situ hybridization of nematodes. It has also been used as a component of isoelectric focusing solution (IEF) to resuspend myofibrils for protein studies.

Warning

Toxicity: Irritant (B)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

324504-ML:
324504-500ML:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

M P Richards et al.
Journal of chromatography, 402, 243-256 (1987-07-31)
Reversed-phase high-performance liquid chromatography (RP-HPLC) was used to isolate, characterize and quantitate liver and kidney metallothionein (MT) isoforms from a variety of animal species. The isoMTs were eluted from a radially compressed C18 column with a neutral sodium phosphate buffer
Amreen Sunil et al.
Cureus, 13(7), e16424-e16424 (2021-07-20)
Psoriasis is a long-term, autoimmune inflammatory condition characterized by red, scaly plaques that can range from a few patches to total skin coverage. Over the past 60 years, and more recently, the metal-chelating agent ethylenediaminetetraacetic acid (EDTA) has proven increasingly
Krishnan MohanKumar et al.
American journal of physiology. Gastrointestinal and liver physiology, 318(4), G705-G716 (2020-02-25)
Anemia is a frequent diagnosis in critically ill infants, but the clinical implications of severe anemia in these patients remain unclear. In this study, we examined preweaned mice to investigate the effects of severe anemia during early infancy on gut
Walter E Knight et al.
STAR protocols, 2(4), 100912-100912 (2021-11-11)
When cultured under typical conditions, human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are structurally and functionally immature. We have previously demonstrated that culture of hiPSC-CMs in maturation medium containing fatty acids, in combination with culture on micropatterned surfaces, produces cells that

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service