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311204

Sigma-Aldrich

Nᴳ,NG′-Dimethyl-L-arginine dihydrochloride

≥97% (HPLC), solid, nitric oxide synthesis inhibitor, Calbiochem®

Synonym(s):

NG,NG′-Dimethyl-L-arginine, Dihydrochloride, SDMA, 2HCl

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About This Item

Empirical Formula (Hill Notation):
C8H18N4O2 · 2HCl
Molecular Weight:
275.18
UNSPSC Code:
12352209
NACRES:
NA.77

product name

NG,NG′-Dimethyl-L-arginine, Dihydrochloride, Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.

Quality Level

100

Assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white to light yellow

solubility

water: 50 mg/mL

shipped in

wet ice

storage temp.

2-8°C

General description

A cell-permeable endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
NOS in vitro
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Other Notes

Nam, S.W., et al. 1998. Arch. Pharm. Res. 21, 128.
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

311204-25MG:
311204-5GM:
311204-0MG:
311204-MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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