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Safety Information

239785

Sigma-Aldrich

Cyclophosphamide Monohydrate

≥98% (HPLC), solid, anti-neoplastic agent, Calbiochem®

Synonym(s):

Cyclophosphamide Monohydrate, N,N- bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA, N,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA

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About This Item

Empirical Formula (Hill Notation):
C7H15Cl2N2O2P · xH2O
CAS Number:
6055-19-2
Molecular Weight:
261.09 (anhydrous basis)
MDL number:
MFCD00149395
UNSPSC Code:
51112507
NACRES:
NA.77

product name

Cyclophosphamide Monohydrate, A widely used anti-neoplastic agent that also displays immunosuppressant properties.

Quality Level

100

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 30 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI key

PWOQRKCAHTVFLB-UHFFFAOYSA-N

General description

A widely used anti-neoplastic agent that also displays immunosuppressant properties. Induces apoptotic cell death in rat thymus through the Fas/Fas ligand pathway.
A widely used antineoplastic agent that also displays immuno-suppressant activity. Induces apoptotic cell death in rat thymus throught Fas/Fas ligand pathway.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Fas/Fas ligand pathway
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

Reconstitution

Solutions should be prepared fresh on the day of use.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Wang, G.J., and Cai, L. 1999. Mutat. Res.427, 125.
Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H340,H350,H360FD

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

239785-GM:
239785-1GM:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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