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233480

Sigma-Aldrich

Coagulation Factor XI, Human Plasma

Coagulation Factor XI, Human Plasma, CAS 9013-55-2, is a native coagulation factor XI with two identical polypeptide chains linked by disulfide bond. It is activated to Factor XIa by Factor XIIa.

Synonym(s):

Coagulation Factor XI, Human Plasma

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About This Item

CAS Number:
9013-55-2
UNSPSC Code:
12352202
NACRES:
NA.77

Quality Level

100

form

liquid

specific activity

≥170 units/mg protein (clotting assay)

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−70°C

General description

Coagulation Factor XI, Human Plasma, CAS 9013-55-2, is a native coagulation factor XI with two identical polypeptide chains linked by disulfide bond. It is activated to Factor XIa by Factor XIIa.
Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80 kDa upon reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.
Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80,000 on reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma
single band by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

233480-100UG:
233480-UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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