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Safety Information

208698-M

Sigma-Aldrich

Calmodulin, Human Brain

Calmodulin, Human Brain, is a ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from human brain.

Synonym(s):

CaM, Ca 2+/Calmodulin, CaM, Ca2+/Calmodulin

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About This Item

UNSPSC Code:
12352202

Quality Level

100

Assay

≥95% (native PAGE)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

storage temp.

−20°C

General description

Calmodulin purifed from human brain.
Calmodulin purifed from human brain. Calmodulin is a ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.

Physical form

Lyophilized from protein solution with 2 mM EDTA.

Reconstitution

Reconstitute with distilled water. H₂O (1 mg/ml)

Other Notes

O′Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci.15, 59.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun.104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

208698-500UG-M:
208698-UG:
208698-500UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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