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16-310

Sigma-Aldrich

Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody

from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity (predicted by homology)

all

technique(s)

immunoprecipitation (IP): suitable

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... NOS1(4842)

General description

Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others.

Immunogen

Nitrated KLH

Application

Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody is an antibody against Nitrotyrosine for use in IP.
Research Category
Signaling
Research Sub Category
General Post-translation Modification

Quality

Evaluated by immunoprecipitation on A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).

Target description

Varies

Physical form

20% slurry; 1x PBS, 0.05% sodium aside.
Sufficient for 10 IPs.
Format: Purified
Immunoaffinity Chromatography

Storage and Stability

Stable for 1 year at 2-8°C from date of shipment. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Analysis Note

Control
A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

16-310:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Andrew Stiff et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 24(8), 1891-1904 (2018-01-25)
Purpose: mAbs are used to treat solid and hematologic malignancies and work in part through Fc receptors (FcRs) on natural killer cells (NK). However, FcR-mediated functions of NK cells from patients with cancer are significantly impaired. Identifying the mechanisms of

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