Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

16-226

Sigma-Aldrich

Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor™ 488 conjugate

clone 1A6, Upstate®, from mouse

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

conjugate

ALEXA FLUOR™ 488

antibody form

purified antibody

antibody product type

primary antibodies

clone

1A6, monoclonal

species reactivity

vertebrates

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable
western blot: suitable

isotype

IgG2bκ

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... NOS1(4842)

Application

This Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 488 conjugate is validated for use in FC, WB for the detection of Nitrotyrosine.

Quality

Routinely evaluated by immunoblot.

Physical form

Protein G Purified mouse monoclonal in a solution of 1% BSA, PBS, 0.05% Tween, and 0.05% sodium azide as a preservative.

Storage and Stability

Stable for 1 year at 2–8°C from date of shipment in undiluted aliquots. Upon receipt, and prior to removing the cap, centrifuge the vial to remove any material in the cap. DO NOT FREEZE. Store at 2–8°C in aliquots, in the dark. Avoid repeated warming/cooling cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

16-226:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Relevance of protein nitration in brain injury: a key pathophysiological mechanism in neurodegenerative, autoimmune, or inflammatory CNS diseases and stroke.
Sarchielli, P, et al.
Amino Acids, 25, 427-436 (2003)
Biological selectivity and functional aspects of protein tyrosine nitration.
Ischiropoulos, Harry
Biochemical and biophysical research communications, 305, 776-783 (2003)
Compartmentalized nitrosation and nitration in mitochondria.
Ghafourifar, Pedram and Colton, Carol A
Antioxidants & Redox Signaling, 5, 349-354 (2003)
Ming-Hui Zou et al.
The Journal of clinical investigation, 109(6), 817-826 (2002-03-20)
Nitric oxide (NO) is produced by NO synthase (NOS) in many cells and plays important roles in the neuronal, muscular, cardiovascular, and immune systems. In various disease conditions, all three types of NOS (neuronal, inducible, and endothelial) are reported to
Zarema Balafanova et al.
The Journal of biological chemistry, 277(17), 15021-15027 (2002-02-13)
Activation of protein kinase C (PKC) epsilon by nitric oxide (NO) has been implicated in the development of cardioprotection. However, the cellular mechanisms underlying the activation of PKCepsilon by NO remain largely unknown. Nitration of protein tyrosine residues has been
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service