Purospher® STAR RP-18 endcapped (5 µm) Hibar® RT 250-4.6

suitable for HPLC

storage conditions

no restrictions.


stainless steel column

Quality Level


suitable for USP L1

product line





1 ea of

extent of labeling

17% Carbon loading


400 bar pressure
65 °C max. temp.


HPLC: suitable
LC/MS: suitable
mass spectrometry (MS): suitable (High)

column L × I.D.

25 cm × 4.6 mm


fully porous particle

matrix active group

C18 bonding phase

particle size

5 μm

pore size

120 Å pore size

surface area

330 m2/g

operating pH range

1.5 - 10.5

separation technique

reversed phase
supercritical fluid (SFC)

storage temp.

no temp limit

Related Categories

General description

HPLC column
Purospher® STAR RP-18 endcapped is the best choice for HPLC separation of basic, neutral, metal chelating samples or indeed any other format. Its outstanding performance and stability, allows a maximum flexibility in method development. Robust methods can be developed across the entire pH spectrum from 1.5 to 10.5 enabling the use of the complete range of mobile phases.

Analysis Note

Pressure: ≤ 130 bar
Theoretical Plates (N/m) (Toluene): ≥ 80000
Symmetry (Toluene): 0.8 - 1.4
Capacity factor (Toluene): 1.0 - 3.0

Legal Information

Hibar is a registered trademark of Merck KGaA, Darmstadt, Germany
Purospher is a registered trademark of Merck KGaA, Darmstadt, Germany


11 - Combustible Solids

Certificate of Analysis

Certificate of Origin

Powdered black pepper was chosen as example for dietary supplements, being a source for pierine. It is tested according to the current United States Pharmacopeia (USP) guidelines using HPTLC and HPLC.
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