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Safety Information

1.08510

SAFC

Vanillin

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

Pharma Manufacturing

Synonym(s):

Vanillin, 4-Hydroxy-3-methoxybenzaldehyde

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About This Item

Linear Formula:
(CH3O)(OH)C6H3CHO
CAS Number:
121-33-5
Molecular Weight:
152.15
MDL number:
MFCD00006942
UNSPSC Code:
12352114
EC Index Number:
204-465-2

Agency

BP
NF
Ph. Eur.

Quality Level

500

vapor pressure

0.0029 hPa ( 25 °C)

product line

EMPROVE® ESSENTIAL

form

solid

autoignition temp.

>400 °C

technique(s)

API processing | cocrystal formation: suitable

pH

4.3 (20 °C, 10 g/L in H2O)

mp

80-83.5 °C

transition temp

flash point 160 °C

solubility

9 g/L

density

1.06 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

15-25°C

InChI

1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3

InChI key

MWOOGOJBHIARFG-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Vanillin is a commonly used ingredient in food and pharmaceutics. In pharmaceutical applications, vanillin has been used primarily as flavor enhancer for oral dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

319.6 - 321.4 °F - closed cup

Flash Point(C)

159.8 - 160.8 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

1085101000:
1085109025:
1085109028:
1085101000BWT:
1085100000:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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