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Key Documents

Safety Information

1.00713

SAFC

Sulfuric acid

95-98%, EMPROVE® ESSENTIAL, Ph. Eur., BP, JPE, NF

Pharma Manufacturing

Synonym(s):

Sulfuric acid

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About This Item

Linear Formula:
H2SO4
CAS Number:
Molecular Weight:
98.08
Beilstein:
2037554
MDL number:
UNSPSC Code:
12352301
EC Index Number:
231-639-5

Agency

BP
JPE
NF
Ph. Eur.
suitable for EPA 1613

Quality Level

vapor density

<0.3 (25 °C, vs air)

vapor pressure

0.0001 hPa ( 20 °C)
1 mmHg ( 146 °C)

product line

EMPROVE® ESSENTIAL

Assay

95-97% (alkalimetric)

form

liquid

concentration

95-98%

technique(s)

API processing | salt formation: suitable

pH

0.3 (25 °C, 49 g/L in H2O)

bp

~290 °C (lit.)

mp

-20 °C

density

1.840 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.0002%
nitrate (NO3-): ≤0.00010%

cation traces

As: ≤0.000010%
Fe: ≤0.0002%
NH4+: ≤0.0005%
Pb: ≤0.0005%
V: ≤0.0002%
heavy metals (as Pb): ≤0.0005%

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation

storage temp.

2-30°C

SMILES string

OS(O)(=O)=O

InChI

1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)

InChI key

QAOWNCQODCNURD-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sulfuric acid can be used as acidifying agent in a variety of pharmaceutical formulations and processes.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

1.00713.1000A:
CH21007139370:
1007131000BWT:
1007139370:
1007132500BWT:
1007139999:
1007139680:
1007131000:
1007132500:
1007130000:
1007139023:
CO1E1007132500:
1007139025:
CO1E1007131000:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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