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Merck
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Key Documents

07-807

Sigma-Aldrich

Anti-phospho-Met (Tyr1003) Antibody

Upstate®, from rabbit

Synonym(s):

c-Met, cmet, HGFR, RCCP2, met proto-oncogene (hepatocyte growth factor receptor)

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_000245.2

UniProt accession no.

P08581

shipped in

dry ice

target post-translational modification

phosphorylation (pTyr1003)

Gene Information

human ... MET(4233)

Specificity

Predicted to cross-react with Mouse and Rat based on complete sequence homology.
Recognizes Met phosphorylated on Tyr1003.

Immunogen

Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-Met (Tyr1003).

Application

Anti-phospho-Met (Tyr1003) Antibody is an antibody against phospho-Met (Tyr1003) for use in WB.

Quality

Routinely evaluated by immunoblot.

Target description

155 kDa

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

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A selective c-met inhibitor blocks an autocrine hepatocyte growth factor growth loop in ANBL-6 cells and prevents migration and adhesion of myeloma cells
Hov, H?kon, et al
Clinical cancer research : an official journal of the American Association for Cancer Research, 10, 6686-6694 (2004)

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