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Key Documents

Safety Information

05-940

Sigma-Aldrich

Anti-INCENP Antibody, clone 58-217

clone 58-217, Upstate®, from mouse

Synonym(s):

Anti-2700067E22Rik, Anti-C130081E20, Anti-C77457

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

58-217, monoclonal

species reactivity

human

should not react with

rat, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NP_064623

UniProt accession no.

Q9NQS7

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... INCENP(3619)

Specificity

INCENP

Immunogen

6His tagged fusion protein corresponding to residues 231-398 of human Inner Centromere Protein (INCENP). Clone 58-217.

Application

Detect INCENP with Anti-INCENP Antibody, clone 58-217 (Mouse Monoclonal Antibody), that has been shown to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Quality

Routinely evaluated by immunoblot.

Target description

135-155kDa

Physical form

Format: Purified
Protein G Purified

Storage and Stability

2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

05-940:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ulrike Gruneberg et al.
The Journal of cell biology, 166(2), 167-172 (2004-07-21)
Mitotic kinases of the Polo and Aurora families are key regulators of chromosome segregation and cytokinesis. Here, we have investigated the role of MKlp1 and MKlp2, two vertebrate mitotic kinesins essential for cytokinesis, in the spatial regulation of the Aurora
Interphase cytofission maintains genomic integrity of human cells after failed cytokinesis.
Choudhary, A; Lera, RF; Martowicz, ML; Oxendine, K; Laffin, JJ; Weaver, BA; Burkard, ME
Proceedings of the National Academy of Sciences of the USA null
Sally P Wheatley et al.
The Journal of biological chemistry, 279(7), 5655-5660 (2003-11-12)
The chromosomal passengers, aurora-B kinase, inner centromere protein (INCENP), and survivin, are essential proteins that have been implicated in the regulation of metaphase chromosome alignment, spindle checkpoint function, and cytokinesis. All three share a common pattern of localization, and it
Reiko Honda et al.
Molecular biology of the cell, 14(8), 3325-3341 (2003-08-20)
The function of the Aurora B kinase at centromeres and the central spindle is crucial for chromosome segregation and cytokinesis, respectively. Herein, we have investigated the regulation of human Aurora B by its complex partners inner centromere protein (INCENP) and
Asha Recino et al.
The Biochemical journal, 430(2), 207-213 (2010-07-16)
RASSF7, a member of the N-terminal Ras association domain family, has increased expression in various cancers and, on the basis of our previous work in Xenopus embryos, may be a regulator of mitosis. In the present study, we address, for

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