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Key Documents

Safety Information

05-682

Sigma-Aldrich

Anti-Mps1 Antibody, NT, clone 3-472-1

clone 3-472-1, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

3-472-1, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_003318

UniProt accession no.

P33981

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... C5AR2(27202)

General description

Mps1 was previously known as TTK/PYK

Application

Detect Mps1 with Anti-Mps1 Antibody, NT, clone 3-472-1 (Mouse Monoclonal Antibody), that has been shown to work in WB.

Quality

routinely evaluated by immunoblot on HeLa total cell extract

Target description

97kDa

Physical form

Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

05-682:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint.
Ballister, ER; Riegman, M; Lampson, MA
The Journal of cell biology null
Mandar R Bhonde et al.
The Journal of biological chemistry, 281(13), 8675-8685 (2006-02-01)
DNA damage induced by the topoisomerase I inhibitor irinotecan (CPT-11) triggers in p53(WT) colorectal carcinoma cells a long term cell cycle arrest and in p53MUT cells a transient arrest followed by apoptosis (Magrini, R., Bhonde, M. R., Hanski, M. L.
Volker M Stucke et al.
The EMBO journal, 21(7), 1723-1732 (2002-04-03)
Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly checkpoint. Here we show that hMps1, the human homolog of yeast Mps1p, is a cell cycle-regulated kinase with maximal activity during M
Adrian T Saurin et al.
Methods in molecular biology (Clifton, N.J.), 1413, 333-347 (2016-05-20)
Mitotic kinetochores are signaling network hubs that regulate chromosome movements, attachment error-correction, and the spindle assembly checkpoint. Key switches in these networks are kinases and phosphatases that enable rapid responses to changing conditions. Describing the mechanisms and dynamics of their
Elodie Montaudon et al.
Nature communications, 11(1), 4053-4053 (2020-08-15)
A significant proportion of patients with oestrogen receptor (ER) positive breast cancers (BC) develop resistance to endocrine treatments (ET) and relapse with metastatic disease. Here we perform whole exome sequencing and gene expression analysis of matched primary breast tumours and
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