05-23-4910

Syntide 2

Phosphate acceptor peptide that serves as a substrate for CaM kinase II and protein kinase C.

• Synonym(s): Syntide 2, Ca²⁺/Calmodulin Kinase II Substrate, PLARTLSVAGLPGKK
• Empirical Formula (Hill Notation): C₆₈H₁₂₂N₂₀O₁₈
• CAS Number: 108334-68-5
• Molecular Weight: 1507.82
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• solubility: 5% acetic acid: 1 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• InChI: 1S/C68H122N20O18/c1-35(2)29-46(83-57(95)42-21-16-26-73-42)60(98)77-40(10)56(94)81-44(22-17-27-74-68(71)72)59(97)87-54(41(11)90)65(103)84-47(30-36(3)4)61(99)85-49(34-89)62(100)86-53(38(7)8)64(102)78-39(9)55(93)75-32-52(92)80-48(31-37(5)6)66(104)88-28-18-23-50(88)63(101)76-33-51(91)79-43(19-12-14-24-69)58(96)82-45(67(105)106)20-13-15-25-70/h35-50,53-54,73,89-90H,12-34,69-70H2,1-11H3,(H,75,93)(H,76,101)(H,77,98)(H,78,102)(H,79,91)(H,80,92)(H,81,94)(H,82,96)(H,83,95)(H,84,103)(H,85,99)(H,86,100)(H,87,97)(H,105,106)(H4,71,72,74)/t39-,40-,41+,42-,43-,44-,45-,46-,47-,48-,49-,50-,53-,54-/m0/s1
• InChI key: NKBRRWBNPNUBDD-TYKVATLISA-N

Description

General description

Phosphate acceptor peptide that serves as a substrate for CaM kinase II (K_m = 12 µM) and protein kinase C (K_m = 11 µM).

Phosphate acceptor peptide that serves as a substrate for CaM kinase II and protein kinase C.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Substrate for CaM kinase II and protein kinase C

Product does not compete with ATP.

Reversible: no

Packaging

Yes

Warning

Toxicity: Standard Handling (A)

Sequence

H-Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Inoue, S., et al. 1995. Biochem. Biophys. Res. Commun. 215, 861.
Hashimoto, Y., et al. 1987. Arch. Biochem. Biophys.252, 418.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable