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Key Documents

Safety Information

01-201

Sigma-Aldrich

Heregulin-β3, Epidermal growth factor (EGF) domain

The Heregulin-β3 protein, Epidermal growth factor (EGF) domain is available in a 100 µg format.

Synonym(s):

EGF Domain

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75

Quality Level

100

form

liquid

manufacturer/tradename

Upstate®

technique(s)

cell culture | mammalian: suitable

input

sample type mesenchymal stem cell(s)
sample type cardiac stem cell(s)

NCBI accession no.

NM_004495.2
NM_013956.2
NM_013957.2
NM_013958.2
NM_013959.2
NM_013960.2
NM_013961.2
NM_013962.2
NM_013964.2

UniProt accession no.

Q02297

shipped in

dry ice

Gene Information

human ... NRG1(3084)

Related Categories

General description

Product Source: Thrombin cleaved GST-fusion protein corresponding to the EGF domain (residues 178-241) of heregulin-beta 3.

Quality

Routinely evaluated by Receptor Activation Analysis.

Physical form

PBS with 30% glycerol. Liquid.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

01-201:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M Alimandi et al.
The EMBO journal, 16(18), 5608-5617 (1997-10-06)
Interleukin-3 (IL-3)-dependent murine 32D cells do not detectably express epidermal growth factor receptors (EGFRs) and do not proliferate in response to EGF, heregulin (HRG) or other known EGF-like ligands. Here, we report that EGF specifically binds to and can be
L M Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(12), 6809-6814 (1998-06-17)
Interleukin 3-dependent murine 32D cells do not detectably express members of the ErbB receptor family and do not proliferate in response to known ligands for these receptors. 32D transfectants were generated expressing human ErbB4 alone (32D.E4) or with ErbB2 (32D.E2/E4).

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