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Safety Information

N-017

Supelco

Normeperidine solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C14H19NO2
CAS Number:
77-17-8
Molecular Weight:
233.31
EC Number:
200-659-6
MDL number:
MFCD00800248
UNSPSC Code:
41116107
PubChem Substance ID:
329818406
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

O=C(OCC)C1(C2=CC=CC=C2)CCNCC1

InChI

1S/C14H19NO2/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12/h3-7,15H,2,8-11H2,1H3

InChI key

QKHMFBKXTNQCTM-UHFFFAOYSA-N

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General description

Normeperidine is a toxic primary metabolite of the opioid analgesic meperidine. This Certified Snap-N-Spike® Solution is suitable for use in pain prescription monitoring, clinical toxicology, urine drug testing, or forensic analysis by LC-MS/MS, LC/MS or GC/MS. Meperidine, a synthetic opioid with effects similar to morphine, is used as a painkiller.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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O-020

Opiate Multi-component Mixture-5 solution, 250 μg/mL each component in methanol, ampule of 1.0 mL, certified reference material, Cerilliant®

M-035

Meperidine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-038

Meperidine-D4 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-020

Normeperidine-D4 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-083

Normeperidine-D4 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Alcohols
Hazardous rank II

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

N-017-1ML:
N-017-CC:

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Certificates of Analysis (COA)

Lot/Batch Number

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M Shen et al.
Fa yi xue za zhi, 15(4), 204-207 (2003-01-23)
Using meperidine abusers as subjects for this study, we detected in hair meperidine and its metabolites normeperidine, N-OCH3-meperidine and N-AC-meperidine. The content of meperidine and normeperidine of 60 abusers were 103 +/- 130 ng/mg and 117 +/- 143 ng/mg respectively.
X Y Hu et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 29(2), 116-121 (1994-01-01)
Analytical methods of GC/FID and GC/MS for identification and determination of meperidine, an analgesic drug, and its metabolites were established. The determination of meperidine spiked in urine was shown to have a good linear relationship in the range of 0.1-8.0
P A Stone et al.
British journal of anaesthesia, 71(5), 738-740 (1993-11-01)
Patient-controlled analgesia (PCA) with i.v. opioids is prescribed increasingly. We report three cases of norpethidine toxicity in patients receiving pethidine by PCA.
M Shen et al.
Fa yi xue za zhi, 13(1), 3-5 (1997-01-01)
In this study, urine concentrations of meperidine and normeperidine after a single therapeutic dose of meperidine in 5 healthy volunteers have been measured and compared the results to those in meperidine addicts. The results showed that there was a significant
Recognizing normeperidine toxicity.
Patricia McDermot
Nursing, 33(3), 24-24 (2003-03-21)
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