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860545P

Avanti

C12 Lactosyl(β) Ceramide (d18:1/12:0)

Avanti Research™ - A Croda Brand 860545P, powder

Synonym(s):

D-lactosyl-β-1,1′ N-lauroyl-D-erythro-sphingosine

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About This Item

Empirical Formula (Hill Notation):
C42H79NO13
CAS Number:
474943-80-1
Molecular Weight:
806.08
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (860545P-25mg)
pkg of 1 × 5 mg (860545P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860545P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI

1S/C42H79NO13/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-31(46)30(43-34(47)26-24-22-20-17-12-10-8-6-4-2)29-53-41-39(52)37(50)40(33(28-45)55-41)56-42-38(51)36(49)35(48)32(27-44)54-42/h23,25,30-33,35-42,44-46,48-52H,3-22,24,26-29H2,1-2H3,(H,43,47)/b25-23+/t30-,31+,32?,33?,35-,36?,37?,38?,39?,40+,41+,42-/m0/s1

InChI key

KNWHKVBHCLQVFX-NKNVVQMUSA-N

Application

C12 Lactosyl(β) Ceramide (d18:1/12:0) or D-lactosyl-β-1,1′ N-lauroyl-D-erythro-sphingosine may be used:
  • as a lipid standard for the quantification of lipid in planarians using mass spectrometry
  • in lipid binding assay to assess the binding of monoclonal antibodies (mAbs)
  • as an internal standard for lipid extraction from mice using Bligh and Dyer procedure

Packaging

5 mL Amber Glass Screw Cap Vial (860545P-25mg)
5 mL Amber Glass Screw Cap Vial (860545P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

860545P-VAR:
860545P-25MG:
860545P-BULK:
860545P-5MG:

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Mithilesh Kumar Jha et al.
Glia, 68(1), 161-177 (2019-08-28)
Schwann cell (SC)-specific monocarboxylate transporter 1 (MCT1) knockout mice were generated by mating MCT1 f/f mice with myelin protein zero (P0)-Cre mice. P0-Cre+/- , MCT1 f/f mice have no detectable early developmental defects, but develop hypomyelination and reduced conduction velocity
Shelly J Krebs et al.
Immunity, 50(3), 677-691 (2019-03-17)
Lineage-based vaccine design is an attractive approach for eliciting broadly neutralizing antibodies (bNAbs) against HIV-1. However, most bNAb lineages studied to date have features indicative of unusual recombination and/or development. From an individual in the prospective RV217 cohort, we identified
David B Iaea et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158609-158609 (2020-01-10)
STARD4, a member of the evolutionarily conserved START gene family, is a soluble sterol transport protein implicated in cholesterol sensing and maintenance of cellular homeostasis. STARD4 is widely expressed and has been shown to transfer sterol between liposomes as well

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