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860474P

Avanti

1-deoxysphinganine-d3

Avanti Research™ - A Croda Brand 860474P, powder

Synonym(s):

1-deoxysphinganine-d3 (m18:0)

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About This Item

Empirical Formula (Hill Notation):
C18H36D3NO
CAS Number:
1246298-31-6
Molecular Weight:
288.53
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 500 μg (860474P-500ug)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860474P

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCC[C@](O)([H])[C@](N)([H])C([2H])([2H])[2H]

General description

1-deoxysphinganine-d3 is a deuterated compound, wherein the three protons of deoxysphinganine are replaced by deuterium. 1-deoxysphinganine is an atypical sphingoid base devoid of a 1-hydroxyl group.

Biochem/physiol Actions

1-deoxysphinganine acts as a biomarker for Type 2 diabetes. It can function as a cytotoxic lipid for insulin producing cells. 1-deoxysphinganine might exhibit toxicity to cancerous cells.

Packaging

5 mL Amber Glass Screw Cap Vial (860474P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

860474P-500UG:
860474P-BULK:
860474P-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that

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