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700149P

Avanti

16:0 cholesteryl-d7 ester

Avanti Research™ - A Croda Brand 700149P, powder

Synonym(s):

cholesteryl-d7 palmitate

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About This Item

Empirical Formula (Hill Notation):
C43H69D7O2
CAS Number:
1416275-32-5
Molecular Weight:
632.11
UNSPSC Code:
41141804
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (700149P-10mg)
pkg of 1 × 25 mg (700149P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 700149P

shipped in

dry ice

storage temp.

−20°C

General description

Cholesteryl palmitate is a cholesteryl ester. 16:0 cholesteryl-d7 ester is the deuterated form of cholesteryl palmitate or 16:0 cholesteryl ester.

Application

16:0 cholesteryl-d7 ester has been used:
  • in plasma sample preparation for tandem mass spectrometry analysis (MS/MS)
  • as an internal standard in mass spectrometry for quantification of nerve lipids from mice
  • as an internal standard in time-of-flight mass spectrometry (TOFMS) for the quantification of serum extracellular vesicles (EVs) lipids
  • as an external calibrator and internal spiking standard in tandem mass spectroscopy measurements
  • in liposome preparation for retinyl ester hydrolase (REH) and cholesteryl esterase activity assay

Biochem/physiol Actions

Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.

Packaging

5 mL Amber Glass Screw Cap Vial (700149P-10mg)
5 mL Amber Glass Screw Cap Vial (700149P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class Code

11 - Combustible Solids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

700149P-VAR:
700149P-25MG:
700149P-BULK:
700149P-10MG:

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Suming Chen et al.
Journal of circulating biomarkers, 8, 1849454419879848-1849454419879848 (2019-10-22)
There is a wide variety of extracellular vesicles (EVs) that differ in size and cargo composition. EVs isolated from human plasma or serum carry lipid, protein, and RNA cargo that provides insights to the regulation of normal physiological processes, and
Mithilesh Kumar Jha et al.
Glia, 68(1), 161-177 (2019-08-28)
Schwann cell (SC)-specific monocarboxylate transporter 1 (MCT1) knockout mice were generated by mating MCT1 f/f mice with myelin protein zero (P0)-Cre mice. P0-Cre+/- , MCT1 f/f mice have no detectable early developmental defects, but develop hypomyelination and reduced conduction velocity
Matias M Vazquez et al.
Redox biology, 36, 101591-101591 (2020-06-13)
Macrophages play a pivotal role in the early stages of atherosclerosis development; they excessively accumulate cholesterol in the cytosol in response to modified Low Density Lipoprotein (mLDL). The mLDL are incorporated through scavenger receptors. CD36 is a high-affinity cell surface

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