700048P

24(R/S),25-epoxycholesterol-d6

Avanti Research^™ - A Croda Brand

• Synonym(s): 26,26,26,27,27,27-hexadeutero-24,25-epoxycholesterol
• Empirical Formula (Hill Notation): C₂₇H₃₈O₂D₆
• CAS Number: 1246302-86-2
• Molecular Weight: 406.67
• UNSPSC Code: 41116107
• NACRES: NA.25

Properties

• description: 24(R/S),25-epoxycholesterol-d6
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (700048P-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

24(R/S),25-epoxycholesterol-d6 is a deuterated side-chain substituted oxysterol.

Application

24(R/S),25-epoxycholesterol-d6 has been used as a primary and deuterated surrogate sterol standard in the quantitative analysis of extracted sterol samples from cultured cells and tissues.

Biochem/physiol Actions

24(S),25-epoxycholesterol maintains cholesterol homeostasis. It modulates hepatic cholesterol metabolism in vivo. 24(S),25-epoxycholesterol is synthesized in the mevalonate pathway. It inhibits sterol regulatory element-binding protein (SREBP) activation.

Deuterated sterol plays a vital role in chemical and biochemical research. It is used as a mechanistic tracer to study the role of steroid hormones in the function and modulation of several physiological processes. Deuterated sterol is also used as reference standards for mass spectrometry. 24(R/S),25-epoxycholesterol-d6 is a deuterium labeled sterol.

Packaging

5 mL Amber Glass Screw Cap Vial (700048P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids