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171204P

Avanti

Heart Extract Polar

Avanti Research™ - A Croda Brand

Synonym(s):

Heart Polar Lipid Extract (Bovine)

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About This Item

CAS Number:
86088-90-6
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 100 mg (171204P-100mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

lipid extracts

shipped in

dry ice

storage temp.

−20°C

General description

Heart Extract Polar comprises the neutral lipid as a major component. Other components include phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine and phosphatidylinositol.
Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.

Application

Heart Extract Polar may be used:
  • in the preparation of lipid bilayer membrane for ion channel ICln reconstitution
  • in preparation of model membranes for flow fluorometry studies
  • as a lipid standard in thin-layer chromatography

Biochem/physiol Actions

The lipids from the bovine heart mitochondria display a higher phospholipid content compared to liver lipids. Lipid extracts from the mammalian tissues like heart, kidney and liver are used in generating model membranes for mimicking real membranes. These lipid extracts also display nonlamellar phases majorly pertaining to hexagonal, cubic, micellar types at physiological temperatures.

Packaging

5 mL Clear Glass Sealed Ampule (171204P-100mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

171204P-VAR:
171204P-100MG:
171204P-BULK:

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Lipid composition of mitochondria from bovine heart, liver, and kidney
Fleischer S, et al.
Journal of Lipid Research, 8(3), 170-180 (1967)
ICln channels reconstituted in heart-lipid bilayer are selective to chloride
Garavaglia M, et al.
Pflugers Archiv : European Journal of Physiology, 443(5-6), 748-753 (2002)
Inorganic mercury and cadmium induce rigidity in eukaryotic lipid extracts while mercury also ruptures red blood cells
Kerek E, et al.
Biochimica et Biophysica Acta - Biomembranes, 1860(3), 710-717 (2018)
Natural lipid extracts and biomembrane-mimicking lipid compositions are disposed to form nonlamellar phases, and they release DNA from lipoplexes most efficiently
Koynova R and MacDonald RC
Biochimica et Biophysica Acta - Biomembranes, 1768(10), 2373-2382 (2007)

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