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Key Documents

Safety Information

L060084

Sigma-Aldrich

Oxidizer

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About This Item

MDL number:
MFCD00677190
UNSPSC Code:
12352200
NACRES:
NA.51

type

for DNA synthesis

product line

Proligo Reagents

concentration

3.9-4.7 g/L iodine (titration)

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General description

Oxidizer solution, containing tetrahydrofuran (THF), pyridine, iodine and water, is applied to oxidize the chemically unstable trivalent phosphorous triester linkage formed in the coupling reaction to a stable pentavalent phosphate triester. Iodine functions as a mild oxidant and water functions as an oxygen donor.

Preparation Note

Tetrahyrofurane/Water/Pyridine/Iodine 90.54/9.05/0.41/0.43 (v/v/v/w)

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-2.0 °F - closed cup

Flash Point(C)

-18.9 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

L060084-200L:

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Certificates of Analysis (COA)

Lot/Batch Number
HMBJ3634
HMBJ3448
HMBJ2857
HMBJ2491
HMBJ2127

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