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Key Documents

Safety Information

L050083

Sigma-Aldrich

Cap B

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.51

product line

Proligo Reagents

impurities

≤200 ppm Water content (Karl Fischer)

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General description

Cap B solution contains tetrahydrofuran (THF), pyridine, and N-methylimidazole (NMI). It is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Packaging

200L stainless steel returnable drum

Preparation Note

Tetrahydrofurane / N-Methylimidazole / Pyridine 8/1/1 (v/v/v)

Other Notes

Cap B solution, containing tetrahydrofuran (THF), pyridine and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

6.1 °F

Flash Point(C)

-14.4 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

L050083-200L:

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Certificates of Analysis (COA)

Lot/Batch Number
HMBJ3596
HMBJ3160
HMBJ3058
HMBJ2796
HMBJ2519

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