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Key Documents

Safety Information

L032080

Sigma-Aldrich

DCI Activator

0.25 M, configured for PerkinElmer, configured for Polygen

Synonym(s):

DCI activator solution

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About This Item

UNSPSC Code:
41116105
NACRES:
NA.21

type

for DNA synthesis
for DNA synthesis

product line

Proligo Reagents

storage condition

dry at room temperature

concentration

29-32 g/L (DCI content, titration)

impurities

≤30 ppm water content (Karl Fischer)
≤30 ppm water content (Karl Fischer)

color

clear
clear

compatibility

configured for PerkinElmer
configured for Polygen

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Preparation Note

Dicyanoimidazole / Acetonitrile 3/100 (w/v)

Other Notes

Activator solution, containing 4,5-dicyanoimidazole (DCI) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step.
The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

41.0 °F

Flash Point(C)

5 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

L032080-200ML:
L880012-06:4548173279404
L032080-6X200ML:4548174010181
L880020-C02-01:
L880020-06:4548173225753

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Certificates of Analysis (COA)

Lot/Batch Number
HMBJ2902
HMBH5018
HMBH3423
HMBG9806V
HMBG7210V

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