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JKA0001

Sigma-Aldrich

Y-PEG40K

average MN 40,000, NHS, amine reactive

Synonym(s):

Y-PEG-NHS

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About This Item

Linear Formula:
((CH3O(CH2CH2O)nCH2CH2)(CH3(CH2CH2O)nCH2CO)NCH2COOC4H4O2N
UNSPSC Code:
12162002
NACRES:
NA.23

Product Name

Y-PEG40K-NHS, average Mn 40,000

form

powder

mol wt

average Mn 40,000

reaction suitability

reactivity: amine reactive

polymer architecture

shape: Y-shape
functionality: monofunctional

General description

Y-shape PEG NHS from JenKem Technology is a Succinimidyl Carboxymethyl Ester with two PEG arms, reactive towards the amino group of lysine(s) on proteins or other biologics. Amine PEGylation with Y-shape PEG NHS can be completed in less than 1hr at pH 7-8. JenKem proprietary Y-shape PEGs are more selective, due to their sterically bulky structure.

Application

Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Legal Information

Product of JenKem Technology

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

JKA0001-1G:
JKA0001-BULK:
JKA0001-VAR:

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Articles

Applications of Y-Shape Peg Derivatives for Drug Delivery

The immune system protects the body from disease by resisting the invasion of foreign molecules into its cells, for example peptides and proteins are hydrolyzed by proteolytic enzymes; nucleic acids are hydrolyzed by nucleases; and most small molecules are eliminated in the liver and kidneys.

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