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Key Documents

Safety Information

G11608

Sigma-Aldrich

Guanidineacetic acid

99%

Synonym(s):

N-Amidinoglycine, N-Guanylglycine, Glycocyamine

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About This Item

Linear Formula:
H2NC(=NH)NHCH2CO2H
CAS Number:
Molecular Weight:
117.11
Beilstein:
1759179
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

mp

300 °C (lit.)

SMILES string

NC(=N)NCC(O)=O

InChI

1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)

InChI key

BPMFZUMJYQTVII-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

G11608-25G:
G11608-VAR:
G11608-BULK:
G11608-100G:


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Saadet Mercimek-Mahmutoglu et al.
Molecular genetics and metabolism, 105(1), 155-158 (2011-10-25)
A 4-year-old female with history of developmental regression and autistic features was diagnosed with guanidinoacetate methyltransferase deficiency at age 21 months. Upon treatment, she showed improvements in her developmental milestones, sensorial-neural hearing loss and brain atrophy on cranial-MRI. The creatine/choline
J Michiels et al.
Poultry science, 91(2), 402-412 (2012-01-19)
Creatine, (CREA) a central constituent in energy metabolism, is obtained from dietary animal protein or de novo synthesis from guanidinoacetic acid (GAA). Especially in all-vegetable diets, supplemental CREA or GAA may restore the CREA availability in tissues, and hence, improve
Rafael Deminice et al.
The Journal of nutrition, 141(10), 1799-1804 (2011-09-02)
The aim of the present study was to examine the effects of creatine supplementation on liver fat accumulation induced by a high-fat diet in rats. Rats were fed 1 of 3 different diets for 3 wk: a control liquid diet
Carla Valongo et al.
Clinica chimica acta; international journal of clinical chemistry, 348(1-2), 155-161 (2004-09-17)
A new gas chromatography-mass spectrometry method for routine quantification of urine creatine and guanidinoacetic acid (GAA) has been developed to provide a fast, reliable and inexpensive metabolic screening. Our method uses a two-step derivatization procedure which involves a reaction with
P E Sijens et al.
Molecular genetics and metabolism, 88(1), 100-102 (2005-12-14)
MR spectroscopy in a patient with argininosuccinate lyase deficiency revealed elevated cerebral guanidinoacetate signals, indicating that the phenomenon of increased levels of this compound in brain tissue is not limited to creatine deficiencies.

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