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Safety Information

D161403

Sigma-Aldrich

5,5-Dimethylhydantoin

97%

Synonym(s):

Fennosurf 300, 4,4-Dimethyl-2,5-dioxoimidazolidine, DMH

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About This Item

Empirical Formula (Hill Notation):
C5H8N2O2
CAS Number:
77-71-4
Molecular Weight:
128.13
Beilstein:
2827
EC Number:
201-051-3
MDL number:
MFCD00005266
UNSPSC Code:
12352100
PubChem Substance ID:
24893496
NACRES:
NA.22

Quality Level

200

Assay

97%

form

crystals

mp

174-177 °C (lit.)

SMILES string

CC1(C)NC(=O)NC1=O

InChI

1S/C5H8N2O2/c1-5(2)3(8)6-4(9)7-5/h1-2H3,(H2,6,7,8,9)

InChI key

YIROYDNZEPTFOL-UHFFFAOYSA-N

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Application

Reactant for synthesis of:
  • N-chloroheterocyclic antimicrobials
  • β-Amino alcohols as inhibitors of antitubercular target N-acetyltransferase
  • Second-generation selective inhibitors of hepatitis C virus NS3 serine protease
  • Rechargeable biocidal cellulose
  • N-chlorohydantoins

Reactant for asymmetric chlorolactonization reactions

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

D161403-VAR:
D161403-100G:
D161403-BULK:
D161403-250G:
D161403-1KG:
D161403-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP9880
MKCP5581
MKCP4364
MKCP4027
MKCP2686

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Shin J Lee et al.
Molecular metabolism, 11, 33-46 (2018-04-14)
Glucagon-like peptide-1 (GLP-1) neurons in the hindbrain densely innervate the dorsomedial hypothalamus (DMH), a nucleus strongly implicated in body weight regulation and the sympathetic control of brown adipose tissue (BAT) thermogenesis. Therefore, DMH GLP-1 receptors (GLP-1R) are well placed to
Anil K Sahdev et al.
Cancer biology & therapy, 18(5), 304-313 (2017-03-31)
Pyrazinoic acid (PA) is structurally similar to nicotinic acid which acts on G-protein-coupled receptor (GPR109A). GPR109A expresses in colonic and intestinal epithelial sites, and involves in DNA methylation and cellular apoptosis. Therefore, it may be assumed that PA has similar
David M Halpin et al.
Respiratory medicine, 128, 28-41 (2017-06-15)
Chronic obstructive pulmonary disease (COPD) and asthma are leading causes of morbidity and mortality. This narrative review provides an appraisal of the pharmacological and clinical characteristics of tiotropium in COPD and asthma, and examines how these compare with other long-acting
Rong Li et al.
Carbohydrate polymers, 92(1), 534-539 (2012-12-12)
The inherent antimicrobial properties and biodegradability of chitosan make it an ideal candidate for antimicrobial materials. In this study, N-halamine precursor 3-glycidyl-5,5-dimethylhydantoin (GH) was synthesized and bonded onto chitosan by a ring opening reaction between chitosan and GH. The chitosan
Martha Cecilia Téllez-Bañuelos et al.
Journal of immunotoxicology, 13(6), 842-849 (2016-08-06)
Endosulfan (ENDO) is a widely used organochlorine (OC) pesticide and persistent organo-pollutant. Epidemiological studies have shown that high levels of OC exposure were related to colorectal cancer (CRC) incidence. The objectives of the present study were to evaluate histological changes
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Global Trade Item Number

SKUGTIN
D161403-1KG4061826738290
D161403-100G4061833560297
D161403-5G

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