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Key Documents

Safety Information

CPG-511

Sigma-Aldrich

Anionic Liposomes

Phosphatidylglycerol (PG)-based - DOPG:DOPC (2:98 molar ratio 10mM)

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

Quality Level

100

composition

Phosphate buffered saline

concentration

10 mM

impurities

2 mol % DOPG
98 mol % DOPC

particle size

100 nm

pH

7.4

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General description

Liposomes are extensively used to study the interaction of proteins, peptides and other molecules with the surface of a lipid membrane. One of the parameters that affects this interaction is the charge of the liposomal membrane. Phosphatidylglycerol (PG) is a negatviely charged molecule. The amount of the negative zeta potential in the liposomes depends on the molar percentage of PG in the formulation. The anionic-phosphatidylglycerol (PG) liposome catalog contains products made from 0.5 up to 100 percent DOPG with various amount of negative zeta potentials. The matrix lipid DOPC used in the formulation does not significantly contribute to the charge of the liposomes.

Application

Drug delivery
Lipid-protein interactions

Storage and Stability

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

Legal Information

Cellsome is a trademark of Encapsula NanoSciences
Product of Encapsula Nanosciences

Disclaimer

For research use only

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

CPG-511-2ML:

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Certificates of Analysis (COA)

Lot/Batch Number

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