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Key Documents

Safety Information

923788

Sigma-Aldrich

HumaTein™ MSC bioink

derived from primary human mesenchymal stem cell culture, suitable for 3D bioprinting applications

Synonym(s):

3D bioprinting, 3DBP, ECM

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.25

Quality Level

100

composition

Bioink lyophilized powder

impurities

<0.12 EU/mg Endotoxin

storage temp.

−20°C

Application

HumaTein™ MSC bioink is based on whole ECM derived from primary human BM-MSC culture, and it′s suitable for 3D bioprinting applications. Whole ECM consists of more than 300 components includes collagen family, laminin, fibronectin, glycosaminoglycans and reserves more than 500 cytokines in balanced composition that regulate cell phenotype and function for tissue homeostasis in development. HumaTein MSC provides a rich ECM environment to promote cellular proliferation. HumaTein MSC contains human extracellular matrix components including collagens, laminin, fibronectin, tenascin, elastin, and a number of proteoglycans and glycosaminoglycans.

The cell culture derived human whole ECM effectively recapitulates tissue micro-environment during development and in organotypic cell culture. It promotes cell growth and migration and has been shown to support the proliferation of many cell types, including human embryonic stem cells, neural stem cells, endothelial cells, MSC, pericytes, fibroblasts, hepatocytes, skeletal muscle cell, smooth muscle cell, and keratinocytes. This cell culture derived human whole ECM is not denatured nor chloroform sterilized. It provides for a more tissue-like environment, due to the 3D folding structure preserved ECM proteins, which provides scaffolding structure for cell attachment, growth and migration.

Legal Information

HumaTein is a trademark of Rokit Healthcare, Inc.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

923788-60MG:
923788-60MG-PW:
923788-30MG-PW:
923788-30MG:
923788-BULK:
923788-VAR:

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