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920444

Sigma-Aldrich

mPEG functionalized gelatin

50% PEGylation, PEG average Mn 1k, gel strength 300 g Bloom

Synonym(s):

PEGylated Gelatin

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About This Item

Linear Formula:
(C32H50N9O12-)m(CH2CH2O)n
UNSPSC Code:
12352201
NACRES:
NA.23

Quality Level

100

form

(solid or chunk(s) or fiber)

mol wt

PEG average Mn 1k

color

white to off-white

storage temp.

2-8°C

Related Categories

Application

mPEG functionalized gelatin is Type A gelatin grafted with PEG that can be used in drug delivery research. Gelatin is a denatured protein that is obtained by hydrolysis of animal collagen. Its biodegradability, biocompatibility, chemical modification potential and cross-linking possibility make gelatin-based nanoparticles (GNPs) a promising carrier system for drug delivery applications. mPEG functionalization has several advantages − prolonged circulation in the body, decreased degradation by metabolic enzymes, and reduction or elimination of protein immunogencity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

920444-1G:
920444-VAR:
920444-BULK:

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Modified gelatin nanoparticles for gene delivery.
Wettig S D, et al.
Int. J. Pharmacol., 554, 224-234 (2019)
A novel smart PEGylated gelatin nanoparticle for co-delivery of doxorubicin and betanin: A strategy for enhancing the therapeutic efficacy of chemotherapy.
Ghorbani M, et al.
Materials Science and Engineering, C, 97, 833-841 (2019)

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