Skip to Content
Merck
All Photos(1)

Key Documents

Safety Information

900863

Sigma-Aldrich

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

≥95%

Synonym(s):

3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol, Hydroxyl diazirine alkyne, Probe building block

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C7H10N2O
CAS Number:
Molecular Weight:
138.17
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22

Quality Level

Assay

≥95%

form

liquid

density

1.08 g/mL

storage temp.

−20°C

SMILES string

OCCC1(N=N1)CCC#C

Application

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

related product

Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

900863-BULK:
900863-VAR:
900863-50MG:


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service