Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

857335

Sigma-Aldrich

(1S,2R)-(+)-Ephedrine hydrochloride

99%

Synonym(s):

(1S,2R)-(+)-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride, (1S,2R)-(+)-2-Methylamino-1-phenyl-1-propanol hydrochloride, D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C6H5CH[CH(NHCH3)CH3]OH · HCl
CAS Number:
24221-86-1
Molecular Weight:
201.69
Beilstein:
6118541
EC Number:
246-090-7
MDL number:
MFCD00064551
UNSPSC Code:
12352116
PubChem Substance ID:
24888441
NACRES:
NA.22

Assay

99%

form

crystals

optical activity

[α]23/D +34.3°, c = 5 in H2O

mp

218-220 °C (lit.)

SMILES string

Cl[H].CN[C@H](C)[C@@H](O)c1ccccc1

InChI

1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10-;/m1./s1

InChI key

BALXUFOVQVENIU-GHXDPTCOSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Ephedrines are quite significant components in asymmetric synthesis; they are commonly used as key components in the preparation of heterocyclic compounds. They are also used as reagents/ catalytic substances or ligands for the synthesis of aryl/heteroaryl derivatives and organometallic complexes.

Application

(1S,2R)-(+)-Ephedrine hydrochloride may be used in the preparation of (R)-methcathinone via permanganate method of oxidation.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

857335-5G:
857335-VAR:
857335-BULK:
857335-25G:
857335-1G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
1447848V
1447848
1167365
06121KE
03112DW

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chiral identification and determination of ephedrine, pseudoephedrine, methamphetamine and metecathinone by gas chromatography and nuclear magnetic resonance.
LeBelle MJ, et al.
Forensic Science International, 71(3), 215-223 (1995)
Metal-Drug Interactions: Synthesis and Spectroscopic Characteristics, Surface Morphology, and Pharmacological Activity of Ephedrine-HCl Complexes with Mo (V), Nb (V), Ga (III), and Ge (IV)
El-Habeeb AA and Refat MS
Russ. J. Gen. Chem., 88(10), 2163-2169 (2018)
An efficient synthesis of aziridines from ephedrines
Cruz A, et al.
Tetrahedron Asymmetry, 21(8), 909-913 (2010)
Noel Kong et al.
Journal of separation science, 37(21), 3015-3023 (2014-08-22)
A sensitive hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry method was developed and validated for the simultaneous detection and quantification of etilefrine and oxilofrine in equine blood plasma and urine. The method is highly sensitive and specific with

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service