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Safety Information

528056

Sigma-Aldrich

Thioglycolic acid

≥99%

Synonym(s):

Mercaptoacetic acid

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About This Item

Linear Formula:
HSCH2COOH
CAS Number:
68-11-1
Molecular Weight:
92.12
Beilstein:
506166
EC Number:
200-677-4
MDL number:
MFCD00004876
UNSPSC Code:
12352100
PubChem Substance ID:
24874663
NACRES:
NA.22

vapor density

3.2 (vs air)

Quality Level

100

vapor pressure

0.4 mmHg ( 25 °C)

Assay

≥99%

autoignition temp.

662 °F

availability

available only in EU

refractive index

n20/D 1.505 (lit.)

bp

96 °C/5 mmHg (lit.)

mp

−16 °C (lit.)

density

1.326 g/mL at 20 °C (lit.)

functional group

carboxylic acid
thiol

storage temp.

2-8°C

SMILES string

OC(=O)CS

InChI

1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)

InChI key

CWERGRDVMFNCDR-UHFFFAOYSA-N

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Application

Thioglycolic acid (TGA) can be used as:
  • A sulfur source and stabilizing agent to synthesize nanocrystalline metal sulfides via hydrothermal reaction. TGA also controls the morphology and particle sizes of nanocrystalline metal sulfides during the process.
  • An effective agglomeration suppressant for the agglomeration of sulfurized mineral pyrite.
  • A reactant to prepare 2,3-disubstituted-thiazolidin-4-one derivatives by one-pot cyclo-condensation reaction with various aldehydes and amines using supported protic acid catalyst.
  • A capping or stabilizing agent to synthesize CdTe quantum dots with controllable photoluminescence wavelengths.

Legal Information

Product of Arkema

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

266.0 °F - closed cup

Flash Point(C)

130 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

528056-5L:
528056-VAR:
528056-18L:
528056-1L:
528056-25ML:
528056-100ML:4548173922799
528056-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
STBL0162
STBK8722
STBK4770
STBK2391
STBK1871

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Effect of oxidation and thioglycolic acid on separation of coal and pyrite by selective oil agglomeration
DRZYMALA J and Wheelock TD
International Journal of Coal Preparation and Utilization, 14(1-2), 1-11 (1994)
Pyrite suppression in oil agglomeration of coal
Drzymala J, et al.
Proceedings, 1005-1008 (1991)
Baofu Han et al.
Colloids and surfaces. B, Biointerfaces, 100, 209-214 (2012-07-07)
Fluorescent carbon dots (CDs) were solvothermaly synthesized in water-glycol medium by using glucose as carbon source and then modified with polyethyleneimine (PEI) for the first time to improve fluorescence quality. The as-prepared CDs were monodispersed sphere particles with a diameter
Markus Aswendt et al.
Nanomedicine (London, England), 10(16), 2499-2512 (2015-08-22)
We validated novel bimodal iron oxide particles as substitute of ferumoxides for efficient labeling of human neural stem cells (NSCs). The dextrane-coated FeraTrack Direct (FTD)-Vio particles have additional far-red fluorophores for microscopic cell analysis. MR relaxometry, spectrophotometric iron determination and
Zhengqing Liu et al.
Analytica chimica acta, 745, 78-84 (2012-09-04)
A novel fluorescent probe for Cu(2+) determination based on the fluorescence quenching of glyphosate (Glyp)-functionalized quantum dots (QDs) was firstly reported. Glyp had been used to modify the surface of QDs to form Glyp-functionalized QDs following the capping of thioglycolic
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