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495212

Sigma-Aldrich

4-Hydroxy-3-nitropyridine

98%

Synonym(s):

3-Nitro-4-pyridinol

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About This Item

Empirical Formula (Hill Notation):
C5H4N2O3
CAS Number:
5435-54-1
Molecular Weight:
140.10
MDL number:
MFCD00128874
UNSPSC Code:
12352100
PubChem Substance ID:
329757469
NACRES:
NA.22

Quality Level

200

Assay

98%

mp

285 °C (dec.) (lit.)

functional group

nitro

SMILES string

Oc1ccncc1[N+]([O-])=O

InChI

1S/C5H4N2O3/c8-5-1-2-6-3-4(5)7(9)10/h1-3H,(H,6,8)

InChI key

YUWOLBZMQDGRFV-UHFFFAOYSA-N

Related Categories

General description

4-Hydroxy-3-nitropyridine can be synthesized by the nitration of 4-hydroxypyridine.

Application

4-Hydroxy-3-nitropyridine may be used in the synthesis of 4-ethoxy-3-nitropyridine by treating with phosphorus pentachloride (PCl5) followed by ethanol. It may also be used to prepare 4-chloro-3-nitropyridine by treating with PCl5-POCl3 (phosphorus oxychloride).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

495212-VAR:
495212-5G:
495212-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
BCBG3258V
BCBD6803V
1433982
50498PJ
16498LJ

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Unambiguous structural assignment of monoanils of 3,4-pyridinediamine via regioselective synthesis.
Dubey PK, et al.
ARKIVOC (Gainesville, FL, United States), 13, 137-144 (2008)
Use of the Graebe-Ullmann reaction in the synthesis of 8-methyl-γ-carboline and isomeric aromatic aza-γ-carbolines.
Alekseev RS, et al.
Chemistry of Heterocyclic Compounds, 48(8), 1235-1250 (2012)

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