Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

440841

Sigma-Aldrich

(1R,2S)-(+)-cis-1-Amino-2-indanol

99%

Synonym(s):

(1R,2S)-(+)-cis-1-Amino-2-hydroxyindane

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C9H11NO
CAS Number:
136030-00-7
Molecular Weight:
149.19
Beilstein:
2803743
MDL number:
MFCD00216656
UNSPSC Code:
12352116
PubChem Substance ID:
24867628
NACRES:
NA.22

Quality Level

200

Assay

99%

form

solid

optical activity

[α]22/D +63°, c = 0.2 in chloroform

optical purity

ee: 99% (GLC)

mp

118-121 °C (lit.)

SMILES string

N[C@H]1[C@@H](O)Cc2ccccc12

InChI

1S/C9H11NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,8-9,11H,5,10H2/t8-,9+/m0/s1

InChI key

LOPKSXMQWBYUOI-DTWKUNHWSA-N

Looking for similar products? Visit Product Comparison Guide

Application

This cis-aminoindanol and its antipode have been used in the preparation of a series of potent HIV-1 protease inhibitory peptides. Also, they have served as chiral ligands in the catalytic asymmetric reduction of prochiral ketones with boranes.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

440841-VAR:
440841-1G:
440841-BULK:
440841-5G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCF2856
BCBZ5228
BCBS1995V
BCBJ4621V
WXBB6699V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S D Young et al.
Journal of medicinal chemistry, 35(10), 1702-1709 (1992-05-15)
A systematic investigation was undertaken to determine the role of the P1' sidechain in a series of hydroxyethylene isostere based inhibitors of HIV-1 protease. Substitution and homologation of the benzyl P1' side chain of the Phe-Phe isostere based pseudo peptides
D'Aniello, F. et al.
The Journal of Organic Chemistry, 59, 3762-3762 (1994)
Askin, D. et al.
The Journal of Organic Chemistry, 57, 2771-2771 (1992)
Dorsey, B.D. et al.
Tetrahedron Letters, 34, 1851-1851 (1993)
Didier, E. et al.
Tetrahedron, 47, 4941-4941 (1991)
View All Related Papers

Chromatograms

application for HPLC

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service