374334
1,1,1,2-Tetrafluoroethane
≥99%
Synonym(s):
HFC-134a
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About This Item
Linear Formula:
FCH2CF3
CAS Number:
Molecular Weight:
102.03
EC Number:
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥99%
bp
−26.5 °C (lit.)
functional group
fluoro
SMILES string
FCC(F)(F)F
InChI
1S/C2H2F4/c3-1-2(4,5)6/h1H2
InChI key
LVGUZGTVOIAKKC-UHFFFAOYSA-N
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General description
1,1,1,2-Tetrafluoroethane is used as a trifluorovinylating agent in organic synthesis. It is identified as a potential refrigerant used in place of chlorofluorocarbons. 1,1,1,2-Tetrafluoroethane can also be used as a solvent and medical propellant for a wide range of applications. It is used to extract materials of natural origin like natural flavors, fragrances, and nutraceuticals.
Application
1,1,1,2-Tetrafluoroethane can be used:
- As a solvent in the preparation of cross-linked polymer microspheres through the dispersion polymerization method.
- As a porogenic solvent in the preparation of porous polymethacrylate monolith via free radical polymerization.
- In the synthesis of trifluorovinyllithium, a key intermediate for the preparation of 2-halo-2,3-dideoxy-arabinose derivatives of biological importance.
Packaging
Supplied in a Sure/Pac™ cylinder and has a brass needle valve with a male 1/4" NPTF outlet thread installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.
Compatible with the following:
Compatible with the following:
Legal Information
Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Press. Gas Compr. Gas
Storage Class Code
2A - Gases
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
ISHL Indicated Name
Substances Subject to be Indicated Names
ISHL Notified Names
Substances Subject to be Notified Names
JAN Code
374334-VAR:
374334-100G:
374334-25G:
374334-BULK:
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Parthiban Selvam et al.
Langmuir : the ACS journal of surfaces and colloids, 22(21), 8675-8683 (2006-10-04)
In situ high-pressure tensiometry and ab initio calculations were used to rationally design surfactants for the 1,1,1,2-tetrafluoroethane-water (HFA134a|W) interface. Nonbonded pair interaction (binding) energies (E(b)) of the complexes between HFA134a and candidate surfactant tails were used to quantify the HFA-philicity
Daniel S Yuan et al.
Nucleic acids research, 33(12), e103-e103 (2005-07-05)
A remarkable feature of the Yeast Knockout strain collection is the presence of two unique 20mer TAG sequences in almost every strain. In principle, the relative abundances of strains in a complex mixture can be profiled swiftly and quantitatively by
Stella Papasavva et al.
Environmental science & technology, 43(24), 9252-9259 (2009-12-17)
In response to recent regulations and concern over climate change, the global automotive community is evaluating alternatives to the current refrigerant used in automobile air conditioning units, 1,1,1,2-tetrafluoroethane, HFC-134a. One potential alternative is 2,3,3,3-tetrafluoropropene (HFC-1234yf, also known as HFO-1234yf). We
P D Levin et al.
British journal of anaesthesia, 92(6), 865-869 (2004-05-04)
1,1,1,2 Tetrafluoroethane is a hydrofluoroalkane (HFA) that is replacing chlorofluorocarbons (CFC) as a medical aerosol propellant in an attempt to reduce damage to the ozone layer. This study compared the effects of HFA- and CFC-based inhalers on four anaesthetic gas
Robson P S Peguin et al.
Langmuir : the ACS journal of surfaces and colloids, 22(21), 8826-8830 (2006-10-04)
A combined computational and experimental approach is used to determine the interfacial thermodynamic and structural properties of the liquid 1,1,1,2-tetrafluoroethane (HFA134a)-vapor and liquid HFA134a-water (HFA134a|W) interfaces at 298 K and saturation pressure. Molecular dynamics (MD) computer simulations reveal a stable
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