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Safety Information

364959

Sigma-Aldrich

N-[Tris(hydroxymethyl)methyl]acrylamide

contains ≤7% KCl, 93%

Synonym(s):

NAT, TRIS-acrylamide

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About This Item

Linear Formula:
H2C=CHCONHC(CH2OH)3
CAS Number:
13880-05-2
Molecular Weight:
175.18
Beilstein:
2081162
EC Number:
237-645-4
MDL number:
MFCD00081045
UNSPSC Code:
12162002
PubChem Substance ID:
24862471
NACRES:
NA.23

Quality Level

100

Assay

93%

form

solid

contains

≤7% KCl

mp

136-141 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(CO)(CO)NC(=O)C=C

InChI

1S/C7H13NO4/c1-2-6(12)8-7(3-9,4-10)5-11/h2,9-11H,1,3-5H2,(H,8,12)

InChI key

MVBJSQCJPSRKSW-UHFFFAOYSA-N

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Application


  • Reactions of dipropilamine with unsaturated surfactants in the model oil–water system: This study investigates the reactions of dipropilamine with N-[tris(hydroxymethyl)methyl]acrylamide, highlighting potential applications in industrial and pharmaceutical processes (Simonian, 2015).

  • Water-dispersible polymer coated silica nanoparticle for turn-on fluorometric detection of Cephalexin: Utilizes N-[Tris(hydroxymethyl)methyl]acrylamide in the synthesis of a polymer to improve the detection capabilities for pharmaceutical applications, showcasing the adaptability of this monomer in enhancing sensor technologies (Sahu et al., 2022).

  • Ultrasound-triggered piezocatalytic composite hydrogels for promoting bacterial-infected wound healing: Features a hydrogel based on N-[tris(hydroxymethyl)methyl]acrylamide for medical applications, particularly in accelerating wound healing, which is crucial for drug delivery systems and tissue engineering (Liu et al., 2023).

  • An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation: Describes the development of a hydrogel incorporating N-[tris(hydroxymethyl)methyl]acrylamide for potential medical use in treating internal wounds, demonstrating the material′s medical applications in a clinical setting (Webb et al., 2022).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

364959-25G:
364959-VAR:
364959-5G:
364959-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP9438
MKCL9589
MKCJ1851
MKBX5161V
MKBT5899V

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M Kozulić et al.
Analytical biochemistry, 163(2), 506-512 (1987-06-01)
We describe in detail the synthesis of an acrylic monomer, N-acryloyl-tris(hydroxy-methyl)aminomethane (NAT), which was successfully used for the preparation of gels for electrophoresis and isoelectric focusing. The polymerization kinetics and transparency of the poly(NAT) gels crosslinked by N,N'-methylenebisacrylamide (Bis) are
Yasmin Spahr et al.
Open forum infectious diseases, 5(5), ofy077-ofy077 (2018-05-22)
Paramyxoviruses include respiratory syncytial virus (RSV), parainfluenza virus (PIV), and human metapneumovirus (MPV), which may cause significant respiratory tract infectious disease (RTID) and mortality after allogeneic hematopoietic cell transplantation (HCT). However, clinical data regarding frequency and outcome are scarce. We
Fabian Leinisch et al.
Free radical biology & medicine, 112, 240-252 (2017-08-02)
Protein oxidation is a frequent event as a result of the high abundance of proteins in biological samples and the multiple processes that generate oxidants. The reactions that occur are complex and poorly understood, but can generate major structural and
Ashish C Shrestha et al.
Transfusion, 56(12), 3086-3093 (2016-10-21)
Hepatitis E virus (HEV) poses a risk to transfusion safety. In Australia, locally acquired HEV is rare and cases are mainly reported in travelers returning from countries endemic for HEV. The risk posed by HEV to transfusion safety in Australia
Sang Hu Kim et al.
mBio, 10(1) (2019-01-31)
Candida auris is an emerging fungal pathogen and a serious global health threat as the majority of clinical isolates display elevated resistance to currently available antifungal drugs. Despite the increased prevalence of C. auris infections, the mechanisms governing drug resistance
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