Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

363596

Sigma-Aldrich

Diethyl phosphoramidate

98%

Synonym(s):

(Diethoxyphosphoryl)amine, Amidophosphoric acid diethyl ester, Diethyl amidophosphonate, Diethyl aminophosphonate, Diethyl phosphorylamide, O,O′-Diethylphosphoramidate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
H2NP(O)(OC2H5)2
CAS Number:
1068-21-9
Molecular Weight:
153.12
MDL number:
MFCD00015676
UNSPSC Code:
12352100
PubChem Substance ID:
24862205
NACRES:
NA.22

Quality Level

100

Assay

98%

bp

140 °C/3 mmHg (lit.)

mp

51-53 °C (lit.)

SMILES string

CCOP(N)(=O)OCC

InChI

1S/C4H12NO3P/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3,(H2,5,6)

InChI key

MCQILDHFZKTBOD-UHFFFAOYSA-N

Related Categories

General description

Diethyl phosphoramidate is a chemical and biological toxin and its ultra-low level detection by Surface-Enhanced Raman Spectroscopy (SERS) is reported. It is reported as chemical warfare simulant.

Application

Diethyl phosphoramidate may be employed as reagent which mimics or imitates the actual chemical warfare agents. It may be used in the preparation of α-aminoalkyl phosphonates, via three-component Mannich type reaction.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

363596-50G:
363596-10G:
363596-BULK:
363596-VAR:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCN2165
MKCB0585V
MKBS4023V
05205EJ
01202KH

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mehmet Yilmaz et al.
Physical chemistry chemical physics : PCCP, 16(12), 5563-5570 (2014-02-12)
The detection of molecules at an ultralow level by Surface-Enhanced Raman Spectroscopy (SERS) has recently attracted enormous interest for various applications especially in biological, medical, and environmental fields. Despite the significant progress, SERS systems are still facing challenges for practical
Surface-enhanced Raman scattering detection of chemical and biological agents using a portable Raman integrated tunable sensor.
Yan F and Vo-Dinh T.
Sensors and Actuators B, Chemical, 121(1), 61-66 (2007)
Surface detection of chemical warfare agent simulants and degradation products.
Kanu AB, et al.
Analytica Chimica Acta, 553(1), 148-159 (2001)
Mannich type reactions of chlorophosphites, phosphoramides and aldehydes (ketones) under solvent-free and catalyst-free conditions-synthesis of N-phosphoramino a-aminophosphonates.
Zhang J, et al.
Green Chemistry, 9(12), 1341-1345 (2007)

Global Trade Item Number

SKUGTIN
363596-50G
363596-10G4061833540602

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service