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Safety Information

360627

Sigma-Aldrich

Poly(vinyl alcohol)

Mw 8,000-10,000, 80% hydrolyzed

Synonym(s):

PAA

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
9002-89-5
MDL number:
MFCD00081922
UNSPSC Code:
12352104
NACRES:
NA.23

Quality Level

200

form

crystals

mol wt

Mw 8,000-10,000

falling ball

2.5-3.5 cP, 4 % in H2O(20 °C)(lit.)

mp

250 °C (482 °F)

density

1.19-1.31 g/cm3

application(s)

advanced drug delivery
filtration

SMILES string

C=CO

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

PVA is a water soluble biocompatible polymer. It minimizes protein adsorption on its surface due to steric stabilization effect, unique solution properties and molecular conformation in aqueous form. The steric repulsion occurs due to osmotic pressure and elastic restoring forces competing with the van der Waal′s attraction between water soluble polymers and protein.

Application

PVA is used:
  • In the cell collection medium for determining cellular function of mouse oocytes and eggs cells.
  • As a coating and stabilizer in the preparation of drug loaded microparticles.
  • In the preparation of biocompatible polymer blends of chitosan and poly (vinyl) alcohol.
  • In the synthesis of bioactive polymer blends of poly(lactic acid)/poly(vinyl-alcohol)-chitosan.
  • In developing chitosan-polyvinyl alcohol-bioactive glass composite membranes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

360627-1KG:
360627-500G:
360627-25G:
360627-VAR:
360627-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM6713
MKCN9370
MKCM6714
MKCL1109
MKCH8831

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Ezequiel de Souza Costa-Júnior et al.
Journal of materials science. Materials in medicine, 20(2), 553-561 (2008-11-07)
In the present work we report the synthesis, characterization, and preliminary biocompatibility of polymer blends based on Chitosan and poly(vinyl alcohol) (PVA) with low degree of hydrolysis and chemically crosslinked by glutaraldehyde for potential application on skin tissue repairing. The
Preparation and characterization of chitosan/poly(vinyl alcohol) chemically crosslinked blends for biomedical applications
Ezequiel S. Costa-Junior, et al.
Carbohydrate Polymers, 76(3) null
Low protein adsorption biomaterials from polymer blends
Ding YS and Qin C
SPE/ANTEC 1996 Proceedings null
Ternary melt blends of poly(lactic acid)/poly(vinyl alcohol)-chitosan
Grande R, et al.
Industrial Crops and Products (2015)
Luisa L S Dias et al.
Biomatter, 1(1), 114-119 (2011-07-01)
The tissue engineering strategy is a new approach for the regeneration of cementum, which is essential for the regeneration of the periodontal tissue. This strategy involves the cell cultures present in this tissue, called cementoblasts, and located on an appropriate
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