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Safety Information

33220

Sigma-Aldrich

Cadaverine dihydrochloride

≥99.0% (AT)

Synonym(s):

1,5-Diaminopentane dihydrochloride, 1,5-Pentanediamine dihydrochloride, Pentamethylenediamine dihydrochloride

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About This Item

Linear Formula:
NH2(CH2)5NH2 · 2HCl
CAS Number:
1476-39-7
Molecular Weight:
175.10
Beilstein:
3611329
EC Number:
216-022-0
MDL number:
MFCD00012527
UNSPSC Code:
12352100
PubChem Substance ID:
57648777
NACRES:
NA.22

Quality Level

200

Assay

≥99.0% (AT)

form

powder

mp

260-262 °C (lit.)
~260 °C (dec.)

functional group

amine

SMILES string

Cl.Cl.NCCCCCN

InChI

1S/C5H14N2.2ClH/c6-4-2-1-3-5-7;;/h1-7H2;2*1H

InChI key

FGNLEIGUMSBZQP-UHFFFAOYSA-N

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General description

Cadaverine dihydrochloride, dihydrochloride salt of cadaverine (a diamine), is a biogenic amine.

Application

Cadaverine dihydrochloride may be used in the cadaverine tolerance test to evaluate the tolerance of Escherichia coli K12 wild-type strain W3110 for cadaverine in chemically defined R/2 medium. It may be used for the crystallization of maltose-binding protein (MBP)-parathyroid hormone receptor (PTH1R) extracellular domain (ECD)-His6 fusion protein. It has been used as standard compound for the chromatographic quantification of biogenic amines in fish tissue samples.
Cadaverine dihydrochloride was used in the preparation of Avena sativa L. leave protoplast.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

33220-1G-F-KC:
33220-BULK-F:
33220-INTR-F:
33220-10G-F:
33220-VAR-F:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB5724
BCBL6699V
1396184
SZBC0620
SZBB2800

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A Altman et al.
Plant physiology, 60(4), 570-574 (1977-10-01)
Protoplasts isolated from Avena sativa L. leaves undergo progressive senescence when incubated aseptically in 0.6 m mannitol with or without added nutrients. This senescence is manifested by morphological deterioration and ultimate lysis of protoplasts, by a decrease in incorporation of
A L Cinquina et al.
Journal of chromatography. A, 1032(1-2), 73-77 (2004-04-07)
Some biogenic amines, such as putrescine, cadaverine, spermidine and histamine, have been found to be useful as quality indices for the decomposition of fish, so research on the simultaneous analysis of various biogenic amines in food is of interest and
Yeong-Deok Kwon et al.
Journal of bioscience and bioengineering, 111(1), 26-30 (2010-09-11)
To understand the responses of Escherichia coli to high succinate stress and to determine the roles of upregulated genes in high succinate tolerance, a continuous culture of wild-type E. coli W3110 was performed for 268 days in a gradually increasing
Augen A Pioszak et al.
The Journal of biological chemistry, 285(16), 12435-12444 (2010-02-23)
The parathyroid hormone receptor (PTH1R) is a class B G protein-coupled receptor that is activated by parathyroid hormone (PTH) and PTH-related protein (PTHrP). Little is known about the oligomeric state of the receptor and its regulation by hormone. The crystal
A R Pereira et al.
Analytical and bioanalytical chemistry, 412(15), 3629-3637 (2020-04-03)
Histamine intolerance results from a disequilibrium of accumulated histamine and the capacity for histamine degradation. An impaired histamine degradation based on reduced DAO activity and the resulting histamine excess may cause numerous symptoms mimicking an allergic reaction. For that, the
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