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Safety Information

307041

Sigma-Aldrich

1-Phenyl-2-pyrrolidinone

99%

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About This Item

Empirical Formula (Hill Notation):
C10H11NO
CAS Number:
4641-57-0
Molecular Weight:
161.20
EC Number:
225-069-6
MDL number:
MFCD00003192
UNSPSC Code:
12352100
PubChem Substance ID:
24858557
NACRES:
NA.22

Quality Level

100

Assay

99%

form

solid

bp

123 °C/0.2 mmHg (lit.)

mp

67-69 °C (lit.)

SMILES string

O=C1CCCN1c2ccccc2

InChI

1S/C10H11NO/c12-10-7-4-8-11(10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2

InChI key

JMVIVASFFKKFQK-UHFFFAOYSA-N

Related Categories

General description

A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

307041-25G:
307041-VAR:
307041-5G:
307041-BULK:
307041-100G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ0241
MKCM6892
MKCL4319
MKCC4001
MKCC0046

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Mark S Duxbury et al.
Biochemical and biophysical research communications, 313(4), 992-997 (2004-01-07)
Blebbistatin is a novel 1-phenyl-2-pyrrolidinone derivative capable of inhibiting non-muscle myosin II activity with a high degree of specificity. We examined the effects of blebbistatin on pancreatic adenocarcinoma cellular migration, invasion, adhesion, and spreading. Blebbistatin dose-dependently inhibited cellular migration and

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