Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

306622

Sigma-Aldrich

4-Chloro-3-fluorophenol

98%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
ClC6H3(F)OH
CAS Number:
348-60-7
Molecular Weight:
146.55
MDL number:
MFCD00042583
UNSPSC Code:
12352100
PubChem Substance ID:
24858492
NACRES:
NA.22

Quality Level

100

Assay

98%

form

solid

bp

84 °C/44 mmHg (lit.)

mp

54-56 °C (lit.)

solubility

chloroform: soluble 50 mg/mL, clear, colorless

functional group

chloro
fluoro

SMILES string

Oc1ccc(Cl)c(F)c1

InChI

1S/C6H4ClFO/c7-5-2-1-4(9)3-6(5)8/h1-3,9H

InChI key

XLHYAEBESNFTCA-UHFFFAOYSA-N

Related Categories

General description

4-Chloro-3-fluorophenol is hydroxylated at both ortho positions to yield different products.

Application

4-Chloro-3-fluorophenol was used in the synthesis of 4-chloro-3-fluoro catechol.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

306622-1G:
306622-BULK:
306622-5G:
306622-VAR:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCH5775
MKBW1019V
MKBW1222V
MKBR6181V
MKBJ8365V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S Peelen et al.
European journal of biochemistry, 227(1-2), 284-291 (1995-01-15)
This study describes the regioselective hydroxylation and the rates of conversion of a series of fluorinated phenol derivatives by phenol hydroxylase from the yeast Trichosporon cutaneum. The natural logarithm of the kcat value for the conversion of the phenolic substrates
L Ridder et al.
European journal of biochemistry, 257(1), 92-100 (1998-11-03)
The influence of various C4/C5 substituents in catechol (1,2-dihydroxybenzene) derivatives on the overall rate of conversion by catechol-1,2-dioxygenase from Pseudomonas putida (arvilla) C1 was investigated. Using catechol, 4-methylcatechol, 4-fluorocatechol, 4-chlorocatechol, 4-bromocatechol, 4,5-difluorocatechol and 4-chloro-5-fluorocatechol, it could be demonstrated that substituents

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service