305995
2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite
97%
Synonym(s):
Bis(diisopropylamino)(2-cyanoethoxy)phosphine
About This Item
Recommended Products
Assay
97%
form
liquid
refractive index
n20/D 1.470 (lit.)
bp
100 °C/0.5 mmHg (lit.)
density
0.949 g/mL at 25 °C (lit.)
functional group
amine
storage temp.
−20°C
SMILES string
CC(C)N(C(C)C)P(OCCC#N)N(C(C)C)C(C)C
InChI
1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3
InChI key
RKVHNYJPIXOHRW-UHFFFAOYSA-N
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Application
- in preparation of prosphoramidite reagent, required for synthesis of 12-mer oligodeoxynucleotide
- as phosphorylating agent in synthesis of 1,2-diacyl-sn-glycerophosphatidylserine
- in situ preparation of deoxyribonucleoside phosphoramidites
- in preparation of 2′-deoxy-2′-fluoro-3′-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-5′-O-(4-methoxytrityl)-4′-thio-β-D-arabinouridine and 1-(3-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-2-deoxy-2-fluoro-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-arabinofuranosyl)-thymine
- as reagent for synthesizing phosphitylated nucleotides
related product
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 3 - Skin Sens. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
119.3 °F - closed cup
Flash Point(C)
48.5 °C - closed cup
Personal Protective Equipment
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
PDSCL
Deleterious substance
FSL
Group 4: Flammable liquids
Type 2 petroleums
Hazardous rank III
Water insoluble liquid
JAN Code
305995-1G:4548173132419
305995-5G:4548173295800
305995-BULK:
305995-VAR:
305995-500MG:4548173132426
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