299251

Sigma-Aldrich

Ammonium-15N chloride

≥98 atom % 15N, ≥99% (CP)

Synonym(s):
15N Labeled ammonium chloride
Linear Formula:
15NH4Cl
CAS Number:
Molecular Weight:
54.48
MDL number:
PubChem Substance ID:

isotopic purity

≥98 atom % 15N

Quality Level

assay

≥99% (CP)

application(s)

bio NMR: suitable
protein expression: suitable

mp

340 °C (subl.) (lit.)

mass shift

M+1

SMILES string

[15NH4+].[Cl-]

InChI

1S/ClH.H3N/h1H;1H3/i;1+1

InChI key

NLXLAEXVIDQMFP-IEOVAKBOSA-N

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Application

Ammonium-15N chloride has been used:
  • as a medium supplement for the incorporation of 15N in sporulation protein, CsfB, for NMR spectroscopy
  • in assaying nitrogen loss in marine sediment
  • for the incorporation of 15N in apolipoprotein A-I for mass spectrum analysis

Packaging

250 mg in glass insert
1, 10, 20, 50, 100 g in glass bottle
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service,.

Biochem/physiol Actions

Ammonium chloride is a component of the nitrogen cycle. Excess of ammonium chloride depletes ATP in astrocytes. Ammonium chloride inhibits the acidification in endosome-lysosome system. It is a hemolysing agent used in the lysis of erythrocytes. Ammonium chloride administration promotes creatinine and urea clearance in rat.

pictograms

Exclamation mark

signalword

Warning

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3077 9 / PGIII

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds?a critical review
Buffet-Bataillon S, et al.
International Journal of Antimicrobial Agents, 39(5), 381-389 (2012)
Anaerobic ammonium oxidation linked to sulfate and ferric iron reduction fuels nitrogen loss in marine sediments
Rios-Del T, et al.
Biodegradation, 29(5), 429-442 (2018)
Journal of the Chemical Society. Chemical Communications, 62-62 (1982)
The Journal of Organic Chemistry, 46, 4296-4296 (1981)
The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro
Haghighat N, et al.
Metabolic Brain Disease, 15(2), 151-162 (2000)
Articles
Solid-state NMR on Larger Biomolecules; Sigma-Aldrich.com
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