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Safety Information

295213

Sigma-Aldrich

Dichlorofluoromethane

98%

Synonym(s):

Freon® 21

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About This Item

Linear Formula:
FCHCl2
CAS Number:
75-43-4
Molecular Weight:
102.92
EC Number:
200-869-8
MDL number:
MFCD00000825
UNSPSC Code:
12142100
PubChem Substance ID:
24857765
NACRES:
NA.22

vapor density

3.57 (vs air)

vapor pressure

1,193 mmHg ( 21 °C)

Assay

98%

autoignition temp.

1022 °F

bp

8.9 °C (lit.)

mp

−135 °C (lit.)

SMILES string

FC(Cl)Cl

InChI

1S/CHCl2F/c2-1(3)4/h1H

InChI key

UMNKXPULIDJLSU-UHFFFAOYSA-N

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Packaging

Supplied in a Sure/Pac™ cylinder and has a brass needle valve with a male 1/4" NPTF outlet thread installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.

Compatible with the following:

Legal Information

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Freon is a registered trademark of E. I. du Pont de Nemours and Company
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC

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Pictograms

Gas cylinderExclamation mark
GHS04,GHS07

Signal Word

Warning

Hazard Statements

H280,H420

Precautionary Statements

P410 + P403 - P502

Hazard Classifications

Ozone 1 - Press. Gas Liquefied gas

Storage Class Code

2A - Gases

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

295213-VAR:
295213-BULK:
295213-500G:
295213-50G:

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Certificates of Analysis (COA)

Lot/Batch Number
SHBC0858V
23796MM
01130EW
07915AH
11529CD

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H Peter et al.
Archives of toxicology, 58(4), 282-283 (1986-04-01)
Inhalation pharmacokinetics of dichlorofluoromethane (CFC 21) and chlorodifluoromethane (CFC 22) were studied in male Wistar rats by use of a closed inhalation chamber system. CFC 21 was readily eliminated via metabolism. However, CFC 22 underwent no detectable metabolism; pretreatment of
Sofie N Delanoye et al.
Journal of the American Chemical Society, 124(25), 7490-7498 (2002-06-20)
Complexes of haloforms of the type HCCl(n)F(3-)(n) (n = 1-3) with dimethyl ether have been studied in liquid argon and liquid krypton, using infrared spectroscopy. For the haloform C[bond]H stretching mode, the complexation causes blue shifts of 10.6 and 4.8
F G Carpenter
The American journal of physiology, 260(3 Pt 2), R540-R545 (1991-03-01)
The minimum ambient partial pressure required to reversibly disrupt conducted responses in myelinated nerve fibers (Pblock) was determined for 11 gases and chloroform. For all but one substance, Pblock was inversely proportional to their nonaqueous solubility; large-diameter fibers were less
H P Cohen et al.
Journal of endodontics, 19(7), 370-373 (1993-07-01)
Sixty-one mandibular molar teeth with clinically manifest pulpitis, which required endodontic therapy, were studied. Twenty-seven subjects received standard inferior alveolar nerve block (IANB) with 2% lidocaine HCI with 1:100,000 epinephrine and 34 subjects received IANB with 3% mepivacaine with no
Huifeng Shan et al.
AMB Express, 4, 48-48 (2014-11-18)
A fermentative enrichment culture (designated DHM-1) that grows on corn syrup was evaluated for its ability to cometabolically biodegrade high concentrations of chloroform (CF), carbon tetrachloride (CT), and trichlorofluoromethane (CFC-11). When provided with corn syrup and vitamin B12 (0.03 mol B12

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